WHAT'S NEW?

I am thrilled to congratulate and celebrate the outstanding achievements of our undergraduate research group, the Project Symphony, at this year's Iona Scholars Day! Our team of dedicated students has worked tirelessly, and their hard work and commitment have truly paid off. The presentations showcased a wide range of impactful research projects that not only demonstrate the academic excellence of our research group members but also their passion for discovery and learning. Each project was a testament to the creativity and hardwork of the Project Symphony research team. One of the most inspiring aspects of the day was seeing how the Project Symphony members engaged with their research topics. Your enthusiasm was contagious, and it was clear that you had developed a deep understanding and appreciation for the chosen fields of topic. I would like to extend my heartfelt congratulations to each member of the Project Symphony members for your exceptional presentations. Your hard work, dedication, and passion for research have truly set you apart, and I am incredibly proud of all that you have accomplished. As I reflect on Iona Scholars Day and look towards the future, I am excited to see where our Project Symphony research group will go next. I have no doubt that you will continue to achieve great things and make meaningful contributions to your field of study. Once again, congratulations to the Project Symphony on a successful Scholars Day! Your hard work, dedication, and passion for research are truly inspiring, and I can't wait to see what you will accomplish next. -Dr. Lee

We are thrilled to announce the publication of our latest research paper titled "Concentration-Dependent Effects of Curcumin on Membrane Permeability and Structure" in the ACS Pharmacology and Translational Science ( https://doi.org/10.1021/acsptsci.4c00093 ) . This publication represents the culmination of years of hard work, dedication, and collaboration within our research group. In this paper, we delve into how phytochemical curcumin interacts with lipid bilayer. Our findings not only contribute to the existing body of knowledge in this field but also have the potential for successful translation of curcumin into effective medicine. We extend our heartfelt thanks to all the members of our research group for their invaluable contributions, and NSF for funding support. We look forward to continuing our research efforts and sharing more exciting discoveries in the future. Stay tuned for further updates from our research group! Go Project Symphony!

The Project Symphony team publishes another research paper in peer-reviewed journal, Journal of Physical Chemistry B The article titled “Differential Effects of Soy Isoflavones on the Biophysical Properties of Model Membranes” is published in Journal of Physical Chemistry B, an American Chemical Society publication. https://pubs.acs.org/doi/10.1021/acs.jpcb.3c08390 This paper is coauthored by nine undergraduates, Jamie Gudyka ('24 Biochemistry), Jasmin Ceja-Vega ('23 Biochemistry), Katherine Ivanchenko (’23 Chemistry), Wilber Perla (’25 Chemistry), Christopher Poust (’25 Chemistry), Alondra Gamez Hernandez ('23 Biochemistry), Colleen Clarke (’23 Chemistry), Shakinah Silverberg (’24 Biology/Chemistry), Escarlin Perez ('22 Biochemistry) with Dr. Sunghee Lee. Congratulations to the Project Symphony!

The diligent work of Project Research team has culminated in a peer-reviewed research publication. This is the proud result of 10 undergraduate coauthors over the span of 3 years. The title of the article is “Aspirin Interacts with Cholesterol-Containing Membranes in a pH-Dependent Manner”, and appears in Langmuir, an American Chemical Society publication. https://pubs.acs.org/doi/10.1021/acs.langmuir.3c02242 This paper is coauthored by ten undergraduates, Michael Krmic (’22 Biochemistry), Escarlin Perez ('22 Biochemistry), Patrick Scollan (’21 Chemistry), Katherine Ivanchenko (’23 Chemistry), Alondra Gamez Hernandez ('23 Biochemistry), Joseph Giancaspro (’21 Biochemistry), Juan Rosario (’21 Biochemistry), Jasmin Ceja-Vega ('23 Biochemistry), Jamie Gudyka ('24 Biochemistry), Riley Porteus ('24 ACS Chemistry), with Dr. Sunghee Lee. Congratulations to the project team!

This summer, Caroline Scott (Class of 2025, ACS Chemistry) joined a globally renowed scientific team in Tokyo to perform research in the field of Biophysical Chemistry. This opportunity was enabled by the NSF Award to Dr. Sunghee Lee for international research collaboration with Professor Shoji Takeuchi of the University of Tokyo. In the past, five students from Dr. Lee’s research group have traveled to Japan for a month-long research project: Peter J. Milianta (Class of 2016, Biochemistry), Michael McGlone (Class of 2017, Physics), Jacqueline Denver (Class of 2017, Biochemistry), Alessandra Armetta (Class of 2018), and Joseph Giancaspro (Class of 2020). Dr. Lee noted, “This is a tremendous opportunity for our students to experience a true intellectual collaboration. Our research partners in Japan are very impressed by our students’ dedication and contribution. After three years of interruption, I am very happy to be able to send an Iona student to Japan again this summer. Caroline has been working diligently on the investigation of electrical property of model cell membranes and her summer experience provided an even greater level of confidence and strength towards her goal in advancing to a PhD program upon graduation from Iona.” Caroline added “This summer I had the amazing opportunity to travel to Tokyo, Japan for 5 weeks to conduct electrophysiological measurement of a model cell membrane. This experience was incredible. Not only did I learn an immense amount of important research skills, but I also got to explore the country of Japan and learn about its culture and history. On the weekends, I even got to hike to the top of Mount Fuji! The most valuable part of my experience in Japan was how much science I learned including how to analyze data and display results in a way that can help organize ideas and discover problems that will lead the research in the right direction. I am extremely thankful to Dr. Osaki and Prof. Takeuchi for welcoming me and guiding me with every step, and Dr. Lee for giving this opportunity and for her continuous support. I will now get to put these skills to use for the rest of my own scientific career, as I aspire to advance to PhD program after Iona.”

A research team of nine undergraduate students mentored by Dr. Sunghee Lee of the Chemistry & Biochemistry Department, have traveled to San Francisco, CA in August, to present their research findings at the National Meeting of the American Chemical Society (ACS). Joining with the international chemistry community, they presented six posters at the Division of Colloid and Surface Chemistry of ACS alongside PhDs and PostDocs from other institutions. Dr. Lee also delivered an oral presentation on the topic of biophysical membrane effects of bioactive molecules, while highlighting how her Iona team of undergraduates work together in harmony to achieve shared goals.  Dr. Lee added “It is a proud moment for me to see our students confidently showcase their research findings, the fruit of countless hours spent in Cornelia Hall for multiple semesters and summers. Their exposure to the international network of scientists at this event will inspire them to pave their own scientific career paths and interests.” Jamie, a rising senior Biochemistry major added “Attending the American Chemical Society Fall 2023 conference in San Francisco, I got to experience other research going on in the different fields of chemistry. Additionally, I got to learn about research my peers are doing as well as graduate and PhD students. The information I took from this conference in addition to the connections I was able to make are is endless. It makes me excited for the future, and reinforced my desire to pursue an MD/PhD degree after graduating.” Chris, a rising junior Chemistry major added “ACS Fall 2023 at San Francisco was an incredible time. I truly appreciated learning about all the various research topics from chemists all across the globe. I really enjoyed speaking to whoever came up to me, as having an in-depth conversation about Raman Spectroscopy is not something I get to do often. I would like to thank Dr. Lee for the opportunity to attend, and all of Project Symphony for making this trip so enjoyable.”

Before we know it, the summer has passed by just like that! It is so true that time flies when you are having fun. Seeing the camaraderie of Project Symphony during summer is nothing like what one can imagine. One may think that spending each summer day in the science lab is intimidating, but working collaboratively as a team with like-minded future scientists makes it something to look forward to. The group name Project Symphony comes from the idea that each of its members work together in harmony to achieve shared goals: to enhance fundamental understanding of the cell membrane and its interactions with bioactive molecules. Our ambitious plan for the summer research has successfully progressed, and we welcomed along the way two high school students, Lucy and Pariss, who made the time in the lab even more fun and productive. Thank you Lucy and Pariss! We will miss you!

Iona University hosted its 14th Annual Scholars Day to celebrate and showcase the scholarship and creative activities of Iona students on Thursday, April 20, 2023. During this milestone event, our group, Project Symphony, presented 14 posters. While the celebration lasts only one day, it is the culmination of the hard work of all Project Symphony members throughout the semester and beyond. Go Project Symphony!

On Saturday, Oct. 15, 2022, a group of young professionals gathered for our first Project Symphony Reunion. These are graduates who participated in NSF-funded research activities since 2009 with Dr. Lee, now contributing to diverse sectors of academia and industry as future leaders. Considering nearly 8 billion people on earth, it is very special that we are connected together through our unique path of Project Symphony at Iona.  As we look back on the past 18 years of Project Symphony, it reminded us how the whole is greater than the sum of its parts, and how much we achieved something that seems “impossible” at first, but we managed to do it. It is all because we are “together” as a harmonious group. Thank you everyone for all your great contribution!